Over hundreds of thousands of years, plants and humans have intricately shaped each other’s evolution. Plants have profoundly influenced our biology, immune systems, and even our consciousness. From the chemical compounds plants use for defense to the essential nutrients they provide, the genetic relationship between plants and humans is a complex dance of mutual adaptation. As we explore these connections, my aim is to highlight how plants have not only been vital resources for human health but have also played a significant role in shaping our biology in profound and often surprising ways.